罗哌卡因联合两种剂量舒芬太尼镇痛用于分娩镇痛效果比较

摘要

Objective To investigate clinical effects differences of ropivacaine combined with two doses of sufentanil on labor analgesia.Methods300 lying-in women with painless childbirth in the period from January 2016 to December 2016 in department of obstetrics in Deqing hospital of traditional Chinese medicine were chosen and randomly divided into two groups including A group (150 cases) with ropivacaine combined with conventional doses of sufentanil for 7.5μg and B group (150 cases) with ropivacaine combined with low doses of sufentanil for 2.5μg;the block onset time of sensory and motor, arrival time at the maximum block level, modified Bromage score, Apgar score, VAS score at different time points and adverse reaction rate of both groups were compared.ResultsTwo groups of maternal sensory and motor block work time and reach the highest block plane comparative differences had no statistical significance.The modified Bromage score of B group were significant better than A group(P<0.05).The adverse reaction rate of B group were significant lower than A group(P<0.05).ConclusionCompared with conventional dosage sufentanil, luo pp paid in combination with low dose used in epidural sufentanil analgesia can obviously reduce the working time, improve the quality of anesthesia and reduce the incidence of adverse reactions, is suitable for clinicians to choose application.%目的 探讨罗哌卡因联合两种剂量舒芬太尼镇痛用于分娩镇痛临床效果差异.方法 选取浙江省德清县中医院产科2016年1月~2016年12月行无痛分娩产妇300例,采用随机数字表法分为A组(150例)和B组(150例),分别给予常规剂量(7.5μg)和低剂量(2.5μg)舒芬太尼与罗哌卡因联用镇痛;比较2组产妇感觉、运动阻滞起效时间、到达最高阻滞平面时间、改良Bromage评分,新生儿Apgar评分,不同时间点VAS评分及不良反应发生率等.结果 2组产妇感觉、运动阻滞起效时间及到达最高阻滞平面时间比较差异无统计学意义;B组产妇改良Bromage评分明显高于A组(P<0.05);B组产妇不良反应发生率明显低于A组(P<0.05).结论 与舒芬太尼常规剂量比较,罗哌卡因联合低剂量舒芬太尼镇痛用于分娩镇痛可明显减少起效时间,提高麻醉质量及降低不良反应发生率.