我院220例药品不良反应报告分析

摘要

目的 分析药品不良反应(ADR)发生的原因与特点,为临床合理用药提供参考.方法 对医院2009年1月至少2011年8月上报的220例药品不良反应报告,按患者年龄、性剐、给药途径、引起药品不良反应的药品种类、涉及器官或系统以及l临床表现等进行统计、分析.结果 220例药品不良反应报告中涉及的药品共有94种,静脉给药较其他给药途径更易发生(占72.27%),抗感染药物引发的比例最高(占44.09%),药品不良反应主要为皮肤及其附件损害(占31.36%).结论 临床必须重视药品不良反应,并做好药品不良反应监测工作,完善相关报告分析制度,确保临床安全、有效、合理用药.%Objective To analyze the reasons and characteristics of the adverse drug reactions (ADR) occurred in hospital to promote rational drug use. Methods Two hundred and twenty cases of ADR reports collected in our hospital from January 2009 to August 2011 were performed the statistical analysis in aspects of age, sex, route of administration, drug categories inducing ADR, involved organs or systems and the clinical manifestations, etc. Results Of 220 cases of ADR reports, the number of involved drug kinds totaled 94. Seventy -two point twenty - seven percent of ADR was induced by intravenous administration and 44. 09% induced by anti - infective drugs. Lesions of skin and the appendants accounted for 31. 36%. Conclusion Great importance should be attached to ADR monitoring in clinic. And the related ADR reporting and analyzing system should be perfected to ensure clinical safe, effective and rational use of drugs.