目的:探讨颅脑损伤早期低钾血症与预后的关系.方法:通过回顾性病例对照研究,比较颅脑损伤早期有无低钾血症、不同程度低钾血症病例预后的差异.结果:低钾血症组GOS评分(4.3±1.4)分低于血钾正常组(5.0±0.0)分,差异有统计学意义(Z=-3.745,P=0.000);血钾正常组与轻度低钾血症组(K+ 3.0～3.5 mmol/L)GOS评分(4.8±0.9)分比较,差异无统计学意义(Z=-2.066,P=0.039,α'=0.017),但中度低钾血症组(K+<3.0 mmol/L)GOS评分(3.5±1.7)分明显低于其余两组(Z=-7.197,P=0.000;Z=-6.483,P=0.000).结论:颅脑损伤早期低钾血症对预后有一定预测意义,血钾<3.0 mmol/L的病例预后较差.%Objective: To explore the relationship between prognosis and early hypokalemia after brain injuries. Methods: The differences between prognosis and varying degrees of hypokalemia after brain injuries were compared by retrospective case-control study. Results: GOS of the hypokalemia group (4.3 ±1.4) scores was significantly lower than that of normokalemic group(5.0±0.0)scores(Z=-3.745, P=0.000). There was no statistical difference of GOS between the normokalemia group and "mild" hypokalemia group (K+ 3.0-3.5 mmol/L) (4.8±0.9) scores (Z=-2.066, P=0.039, a'=0.017), while that of the "moderate" hy pokalemia group (K+<3.0 mmol/L) (3.5 + 1.7) scores was significantly lower than that of the other two groups (Z=-7.197, P= 0.000; Z=-6.483, P=0.000). Conclution: Early hypokalemia after brain injuries is a predictive index of prognosis. Patients with serum potassium less than 3.0 mmol/L trend to have unfavourable outcome.
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