健康教育路径在肿瘤化疗患者中应用效果的Meta分析

摘要

Objective To systematically evaluate the application effect of the health education pathway on cancer patients with chemotherapy.Methods Studies of the randomized controlled trials of health education pathway on cancer patients receiving chemotherapy were researched in databases from establishment of the databases to December 2016,including Wanfang databases,CNKI,VIP.RevMan 5.3 software was used for statistical analysis.Results Twenty-four literatures and 2 494 patients had been incorporated into this project,including 1242 cases in health education pathway group and 1252 cases in the control group.The results of Meta analysis showed that the mastering of health knowledge (RR =1.36,95％CI:1.22-1.51,P ＜ 0.01),patients'satisfaction (RR =1.19,95％CI:1.12-1.26,P ＜ 0.01) in the health education pathway group were higher than those of control group,the anxiety score (SMD=-1.90),95％CI:-2.44-1.37,P ＜ 0.01) and phlebitis incidence (RR =0.20,95％CI:0.05-0.77,P ＜ 0.05) were lower than those of control group,with statistically significant differences.Conclusion The health education pathway has a better implementation effect compared with traditional health education,but it is still required for verification through multicenter and large sample randomized clinical trials.%目的 系统评价健康教育路径在肿瘤化疗患者中的应用效果.方法 检索万方数据库、中国知网、维普网数据库,收集有关健康教育路径干预肿瘤化疗患者的随机对照试验,同时辅以手工检索,从建立数据库到2016年12月.采用RevMan 5.3统计软件进行统计分析.结果 共纳入24篇文献,包括2494例肿瘤化疗患者,其中观察组1242例,对照组1252例.Meta分析结果显示,健康教育路径组患者健康知识掌握度(RR=1.36,95％CI:1.22～1.51,P＜ 0.01)、护理满意度(RR=1.19,95％CI:1.12～1.26,P＜ 0.01)均优于传统健康教育组,焦虑评分(SMD=-1.90,95％CI:-2.44～-1.37,P＜ 0.01)、静脉炎发生率(RR=0.20,95％CI:0.05～0.77,P＜0.05)均低于传统健康教育组,差异均有统计学意义.结论 健康教育路径在肿瘤化疗患者中应用效果明显优于传统健康教育模式,但仍需多中心、大样本的随机对照试验予以证实.