多种血清标记物联合检测对肝癌早期诊断的临床价值

摘要

Objective To investigate the value of combined detection of multiple serum markers in early diagnosis of primary liver cancer.Methods Selected 100 HCC patients with hepatocellular carcinoma group,100 cases of liver cirrhosis patients with cirrhosis,100 cases of patients with hepatitis B in the group,and selected 100 cases of healthy persons in the control group,comparative analysis of patients in each group were AFP,CEA and Golgi membrane protein 73.ResultsThe serum levels of AFP,CEA and GP73 in HCC patients were higher than those in the other three groups (P<0.05).Conclusion The combined detection of several serum markers has a certain clinical value in the early diagnosis of liver cancer.%目的：探讨多种血清标记物联合检测对原发性肝癌的早期诊断价值。方法选取肝癌患者100例为肝癌组，100例肝硬化患者纳入肝硬化组，100例肝炎患者纳入肝炎组，并选取100例同期健康体检人员纳入对照组，比较分析各组患者甲胎蛋白、癌胚抗原、和高尔基体膜蛋白73水平。结果肝癌组患者AFP、CEA和GP73血清水平均高于其他三组（P＜0.05）。结论多种血清标记物联合检测对肝癌的早期诊断有一定临床价值。