食用香料3-辛酮的合成

摘要

以乙基溴化镁和正己醛为原料，经亲核加成反应合成了3-辛醇，产率为81.2%；采用 PCC对3-辛醇进行氧化得到了食用香料3-辛酮，产率为85.3%。通过气相色谱、红外光谱、色质联机和核磁共振等分析数据对所合成的中间体和目标产物的结构进行了确定；对合成的3-辛酮进行了香气评价。%3-Octanol is synthesized by the nucleophilic addition reaction of ethylmagnesium bromide with n-hexanal,and the yield of 3-octanol is 81.2%.Then flavoring agent 3-octanone is obtained by the oxidation of 3-octanol with PCC,and the yield of 3-octanone is 85.3%.The structures of synthet-ic intermediates and target products are identified by means of GC,IR,GC-MS,1 H NMR and 13 C NMR.The aroma characteristics of 3-octanone are evaluated.