2-取代-5-吡唑基-1，3，4-恶二唑类化合物的合成及生物活性

摘要

A series of 2-pyrazolyl-5-substituted-1,3, 4-oxadiazoles were synthesized starting from 5pyrazole formic acid hydrazide and carboxylic acid by one pot method in the presence of phosphorus oxychloride. Two 1-benzoyl-2-pyrazolylhydrazines were prepared from 5-pyrazole hydrazide. Preliminary bioassay indicated that some compounds showed certain fungicidal and herbicidal activities.%以5-吡唑甲酰肼和取代羧酸为起始物，运用"一锅煮"法合成了一系列2-取代-5-吡唑基-1，3，4-二唑.此外，还合成了1-苯酰基-2-吡唑酰基肼.初步生物活性测定结果表明，部分化合物有较好的杀菌和除草活性.