Synthesis, antimicrobial and antitubercular activity of some novel [3-isonicotinoyl-5-(4- substituted)-2,3-dihydro-1,3,4-oxadiazol-2- yl] and substituted 5-(pyridin-4-yl)-1,3,4-oxadiazole-2-thiol derivatives

摘要

A series of aryloxadiazole and mercaptooxadiazoles have been synthesized and evaluated for antibacterial, antifungal and antitubercular activities. The newly synthesized compounds have been characterized by IR,~1H NMR and elemental analyses. All the compounds have shown promising antibacterial, antifungal and antitubercular activity when compared with standard drug Ciprofloxacin, Griseofulvin and Streptomycin respectively.