首页> 中文期刊> 《生物技术通报》 >植物病理学领域蛋白乙酰化修饰研究进展

植物病理学领域蛋白乙酰化修饰研究进展

         

摘要

蛋白质乙酰化是一种普遍存在于真核与原核生物中且可逆的翻译后修饰方式,由乙酰基转移酶和去乙酰化酶共同调控,参与了转录、新陈代谢、细胞信号转导、细胞凋亡等多个生物学过程.随着检测技术的不断发展,目前已发现了大量的组蛋白及非组蛋白的乙酰化修饰,对其功能的研究也取得一定的进展.本文从乙酰化修饰研究进程出发,对植物病理学领域,包括植物抗病相关过程、植物病原菌和生防菌三个方面的乙酰化研究进展进行总结归纳,并对今后乙酰化修饰研究所需解决的问题进行了展望和讨论.%Protein acetylation is a ubiquitous and reversibly regulated protein post-translational modification in both eukaryotes and prokaryotes, which is regulated by lysine acetyltransferases and lysine deacetylases. It was involved in a variety of biological processes, including transcription, central metabolism, cell signalling and apoptosis. The detection technology of acetylation has developed rapidly and a large number of histone and non-histone proteins have been identified so far. Functional analysis of these acetylated proteins have also made certain progresses. This review summarizes the research status of protein acetylation in plant pathology, including plant disease resistance processes, plant pathogens and biocontrol bacteria. Moreover, future directions as well as the prospects of protein acetylation research were discussed.

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