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Fabrication and study of AC electro-osmotic micropumps.

机译:交流电渗透微型泵的制造和研究。

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摘要

In this thesis, microelectrode arrays of micropumps have been designed, fabricated and characterized for transporting microfluid by AC electro-osmosis (ACEO). In particular, the 3D stepped electrode design which shows superior performance to others in literature is adopted for making micropumps, and the performance of such devices has been studied and explored. A novel fabrication process has also been developed in the work, realizing 3D stepped electrodes on a flexible substrate, which is suitable for biomedical use, for example glaucoma implant.;There are three major contributions to ACEO pumping in the work. First, a novel design of 3D "T-shaped" discrete electrode arrays was made using PolyMUMPsRTM process. The breakthrough of this work was discretizing the continuous 3D stepped electrodes which were commonly seen in the past research. The "T-shaped" electrodes did not only create ACEO flows on the top surfaces of electrodes but also along the side walls between separated electrodes. Secondly, four 3D stepped electrode arrays were designed, fabricated and tested. It was found from the experiment that PolyMUMPsRTM ACEO electrodes usually required a higher driving voltage than gold electrodes for operation. It was also noticed that a simulation based on the modified model taking into account the surface oxide of electrodes showed a better agreement with the experimental results. It thus demonstrated the possibility that the surface oxide of electrodes had impact on fluidic pumping. This methodology could also be applied to metal electrodes with a native oxide layer such as titanium and aluminum. Thirdly, a prototype of the ACEO pump with 3D stepped electrode arrays was first time realized on a flexible substrate using Kapton polyimide sheets and packaged with PDMS encapsulants. Comprehensive experimental testing was also conducted to evaluate the mechanical properties as well as the pumping performance. The experimental findings indicated that this fabrication process was a promising method to create flexible ACEO pumps that can be used as medical implants and wearable devices.
机译:本文设计,制造和表征了微型泵的微电极阵列,用于通过交流电渗透(ACEO)传输微流体。特别地,采用在文献中显示出优于其他文献的性能的3D阶梯式电极设计来制造微型泵,并且已经研究和探索了这种装置的性能。工作中还开发了一种新颖的制造工艺,在柔性基板上实现3D阶梯式电极,适用于生物医学用途,例如青光眼植入物。ACEO泵浦工作有三大贡献。首先,使用PolyMUMPsRTM工艺对3D“ T形”离散电极阵列进行了新颖的设计。这项工作的突破在于离散化连续3D阶梯式电极,这在过去的研究中很常见。 “ T形”电极不仅在电极的顶表面上产生ACEO流动,而且沿分离的电极之间的侧壁产生ACEO流动。其次,设计,制造和测试了四个3D阶梯式电极阵列。从实验中发现,PolyMUMPsRTM ACEO电极通常需要比金电极更高的驱动电压才能进行操作。还应注意的是,基于改进模型的模拟考虑了电极的表面氧化物,显示出与实验结果更好的一致性。因此证明了电极的表面氧化物影响流体泵送的可能性。该方法也可以应用于具有天然氧化物层的金属电极,例如钛和铝。第三,首次使用Kapton聚酰亚胺片在柔性基板上实现了带有3D阶梯状电极阵列的ACEO泵的原型,并用PDMS密封剂包装。还进行了全面的实验测试,以评估机械性能以及泵送性能。实验结果表明,这种制造工艺是制造可用作医疗植入物和可穿戴设备的柔性ACEO泵的有前途的方法。

著录项

  • 作者

    Guo, Xin.;

  • 作者单位

    Queen's University (Canada).;

  • 授予单位 Queen's University (Canada).;
  • 学科 Engineering Materials Science.;Engineering Mechanical.
  • 学位 Ph.D.
  • 年度 2013
  • 页码 155 p.
  • 总页数 155
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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