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AlGaN/GaN HEMT Based Biosensor

机译:基于AlGaN / GaN HEMT的生物传感器

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摘要

GaN has been considered as a promising candidate for biosensing due to its chemical and thermal stability. In this work, an AlGaN/GaN high electron mobility transistor (HEMT) wafer with a 2DEG mobility of 1300 cm~2/v-s and a sheet carrier density of l×10~(13) cm~(-2) was used as a sensor platform. Ti/Al/Ni/Au were used as source and drain contacts, with Ni/Au contacts as gate electrodes. A NF_3 plasma was used for device isolation. Photodefinable PDMS was used for the purpose of encapsulation. Once the encapsulation was completed using the photodefinable PDMS, the Schottky contact was exposed to a thiolated DNA in immobilization buffer for a period of 12hours. XPS was used to confirm the probe immobilization. The change in the (I_d-V_(ds)) characteristics of the device is measured during these processes, which confirm the probe immobilization and also the probe and the target DNA hybridization.
机译:GaN由于其化学和热稳定性而被认为是生物传感的有前途的候选者。在这项工作中,使用具有2DEG迁移率1300 cm〜2 / vs和片载流子密度为1×10〜(13)cm〜(-2)的AlGaN / GaN高电子迁移率晶体管(HEMT)晶片作为衬底。传感器平台。 Ti / Al / Ni / Au用作源极和漏极触点,而Ni / Au触点用作栅电极。 NF_3等离子体用于设备隔离。可光定义的PDMS被用于封装的目的。使用可光定义的PDMS完成封装后,将肖特基触点暴露在固定化缓冲液中的硫醇化DNA中12小时。 XPS用于确认探针固定。在这些过程中测量了设备的(I_d-V_(ds))特性的变化,这证实了探针的固定以及探针与目标DNA的杂交。

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