Electrospinning of Chitosan and its Correlation with Degree of Deacetylation and Rheological Property

摘要

From the SEM results, below the entanglement concentration (1.8 wt%), only beads had formed and above this concentration, the electrospinning was not possible because of the viscous nature of solution. The average fiber diameter increased with the increased in chitosan concentration for DD-90% and also it showed larger distribution of fibers. Chitosan-TFA solutions of 6 wt% was been successfully electrospun onto the Seprafilm™ showing nearly defect free chitosan nanofibers with different degrees of deacetylation. This could be an excellent example of biomedical product that could be use as a barrier film with chitosan nanofiber layer on it for the treatment of post surgical adhesion with fast wound healine rates.