Synthesis and Evaluation of Fluorescent Sugar Recognition ProbesHaving Anthracene Fluorophore with Alkyl Spacer

摘要

Sugar recognition sensors are important.Especially,development of chemical sensors withartificial molecules has attracted much attention.In our laboratory,we have developed complexof γ-cyclodextrin (γ-CyD) and sugar recognition probe possessing pyrene or anthracene asfluorescent moiety.In the systems without spacer between fluorescent moiety andphenylboronic acid (C0-APB or C0-AAB/γ-CyD),sugar recognition function exhibiteddifferent behavior depending on fluorescent moiety).Also,in the pyrene system,sugarrecognition behavior changed significantly by introducing spacer between pyrene andphenylboronic acid).The purpose of this study is to design of a novel fluorescent probepossessing alkyl spacer and anthracene,and to evaluate its sugar recognition function of C1-AAB/CyD complex (Fig.1).