Finding Proteins Whose Expression Levels Depend on Bloodline in Wagyu

摘要

Wagyu is known as beef brand with marbling character, in which the lineage of sires is significantly important to provide quality beef continuously. Sires of Wagyu have been improved through the dedicated efforts of inbreeding, to obtain excellent genetic ability to yield quality beef. In this decade, rapid growth of the technologies to analyze genes and proteins brings us a chance to improve the quality of beef using more direct and precise tools and knowledge. Tremendous amount of relations among genes, proteins, and traits have been clarified, and the knowledge can be potentially utilized to improve the quality of beef. However, there is scarcely a method that analyze bloodlines of sires and cattle to connect bloodline to genes and proteins. In this paper, we newly propose a method to treat bloodline of livestock animals on computers, and to find proteins whose expression levels have strongly related to the bloodline of cattle. With the proposed method, we firstly have a mean to know the relation between bloodline and proteins.