Search for novel chemical warfare agents exposure biomarkers using LC-MS/MS.

机译：搜索使用LC-MS / MS的新型化学战代理曝光生物标志物。

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(1) Quantification method of ion peak areas of BSA tryptic digest peptides was established. (2) 12 peptides which ion peak areas were decreased by adding mustard gas were confirmed. (3) The most prominent peptide was "~(21)GLVLIAFSQYLQQCPFDEHVK~(41)". (4) MS~(2) analysis revealed that HD bound to Cys-34.

机译：（1）建立了BSA胰蛋白酶消化肽的离子峰面积的定量方法。（2）通过添加芥子气体降低离子峰面积的12个肽。（3）最突出的肽是“〜（21）GlvliaFsqylqcpfdehvk〜（41）”。（4）MS〜（2）分析显示HD与CYS-34结合。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2011年||共2页
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Koichiro Tsuge; Mieko Kanamori-Kataoka; Isaac Ohsawa; Takafumi Sato; Takeshi Ohmori; Yasuo Seto;
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Search for novel chemical warfare agents exposure biomarkers using LC-MS/MS.

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