Effect of Tyrosine Position on the Fragmentation Reactions of b3 Ions from Model Tripeptides

摘要

The fragmentation reactions of b3 ions from simple tripeptides have been clearly affected by the position of tyrosine residue within the sequence, in particular the intensity of a3 ion significantly enhanced when the tyrosine is positioned at the C-terminal. This aspect can be explained by stabilizing effect of tyrosine side chain, at least two glycine containing tripeptides.