Control of HIV Infection Dynamics by the Enhancement of the Immune System

摘要

The human immunodeficiency virus infection, that causes acquired immune deficiency syndrome, is a dynamic process that can be modeled via differential equations. In this paper a control method to boost the response of the immune system by means of drug scheduling is introduced. The control purpose is to steer the system to an equilibrium condition, known as long-term nonprogressor, which corresponds to an infected patient that does not develop the symptoms of acquired immune deficiency syndrome. To show the feasibility of the control methodology a human immunodeficiency virus model is studied analytically and computer simulations are presented.