STREPTOMYCES COELICOLOR - ASSOCIATED BRONCHOPNEUMONIA IN PIGS

摘要

Streptomyces infections are uncommonly diagnosed in veterinary medicine except for actinomycetoma in cats caused by Streptomyces griseus (1). In humans, Streptomyces species are known to produce actynomicetomas and other processes in immunocompetent hosts (2, 3). Pneumonia caused by invasive Streptomyces species has been rarely described and often this process has been associated with AIDS (4). The present report deals with three cases of pneumonia in which S. coelicolor was isolated from lungs of circovirus and/or PRRS-infected pigs. During the months previous to the case the farm had been suffering slowered growth rates and a high incidence of poliarthritis and respiratory problems in weaners. Previous diagnosis of post-weaning multisystemic wasting syndrome (PMWS) had been made based on clinical and pathological findings and also by in situ hybridization against porcine circovirus. Routine vaccines comprised PRRS, Aujeszky's disease virus, Mycoplasma hyopneumoniae, P. multocida toxin and H. parasuis. Three pigs (identification number 1, 2 and 3) ranging from 10 to 18 Kg live weight (approximately 5-8 weeks old) were submitted to the Veterinary Faculty of Barcelona as representative of the farm problems.All three pigs showed respiratory difficulty, swollen tarsal joints and very poor corporal condition. After humanitary euthanasia, detailed necropsies were performed. Major macroscopic lesions observed were swollen joints filled with a dark fluid, enlarged inguinal and mesenteric lymph nodes, fibrinous exsudate in the peritoneum and a kidney surface with whitish spots. Pleural adherences were also observed and lungs showed multifocally distributed areas of consolidation.