Biomimetic Mineralization of Dense Collagen Substrates Derived from Demineralized Manatee Bone

摘要

Using a biogenic collagen scaffold obtained from demineralized manatee bone, it was demonstrated that a bone-like nanostructure (intrafibrillar mineral) and microstructure (lamellar osteons) could be restored using the PILP mineralization process. The results of this work lead us closer to the development of bone-like composites that could become the next generation of synthetic bone grafts.