DEMINERALIZED BONE MATRIX (DBM) COMPLEX CONTAINING BONE-DERIVED MINERALS AND MANUFACTURING PROCESS THEREOF

摘要

The present invention relates to a method for producing a composite demineralized bone composition using a one-step process. The composite demineralized bone composition according to the present invention is prepared from bio-derived bone. In addition, the composite demineralized bone composition prepared by the present invention contains bone minerals in the composition in the original composition ratio of bone, and can provide a condition for the content of bone minerals closest to the environment in which bone formation occurs in the body. In addition, by including the bone morphogenetic protein (BMP-2), it is possible to elicit a stable and excellent bone formation effect.