首页> 外文会议>International conference on simulation and modelling in the food and bio-industry >OPERATING CONDITIONS OF A SIMULATED MOVING BED CHROMATOGRAPHY UNIT FOR THE PURIFICATION OF FRUCTO-OLIGOSACCHARIDES
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OPERATING CONDITIONS OF A SIMULATED MOVING BED CHROMATOGRAPHY UNIT FOR THE PURIFICATION OF FRUCTO-OLIGOSACCHARIDES

机译:模拟移动床层析装置纯化果糖寡糖的操作条件

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Dowex Monosphere 99K/320 was found to be more suitable to work in the SMB unit as compared to Dowex 50W-X2 due to greater resistance at high pressure. Batch experiments were carried out to estimate the adsorption parameters. The experimental results are compared with model prediction. The latter is computed by numerical solution of the mass balance equations of a kinetic model, using a method of lines approach and slope limiters for approximating the spatial operators. Indeed, very sharp concentration profiles travel trough the column and non-oscillatory schemes are necessary to avoid spurious oscillations and unrealistic negative concentration values.
机译:发现Dowex Monosphere 99K / 320与Dowex 50W-X2相比,更适合在SMB单元中使用,因为其在高压下的阻力更大。进行批处理实验以估计吸附参数。将实验结果与模型预测进行比较。后者是通过动力学模型的质量平衡方程的数值解来计算的,其中使用了线逼近法和斜率限制器来近似空间算子。确实,非常尖锐的浓度分布曲线会穿过色谱柱,因此必须采用非振荡方案,以避免杂散振荡和不切实际的负浓度值。

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