Novel Biosensor Based on MOSFET-BJT Hybrid Mode of Gated Lateral Bipolar Junction Transistor for C-reactive Protein Detection

摘要

In this paper, a biosensor based on a gated lateral bipolar junction transistor (BJT) was proposed. The gated lateral BJT can function as both a metal-oxide-semiconductor field-effect transistor (MOSFET) and a BJT. By using selfassembled monolayer (SAM) method, the CRP antibodies were immobilized on the floating gate of the device as the sensing membrane. Through the experiment, the characteristics of the gated lateral BJT for biomaterials detection were analyzed in this study. According to the results, under the MOSFET-BJT hybrid mode of the device, when the base current was -10 µA, the sensitivity was approximately 0.80 µA/decade, and the sensing limit was approximately 1 pmol/L. Meanwhile, the gated lateral BJT can be successfully applicable as sensitive biosensor.