首页> 外国专利> INHIBITOR OF NON-SPECIFIC BINDING OF NUCLEIC ACID, HYBRIDIZATION REAGENT AND NUCLEIC ACID HYBRIDIZATION METHOD

INHIBITOR OF NON-SPECIFIC BINDING OF NUCLEIC ACID, HYBRIDIZATION REAGENT AND NUCLEIC ACID HYBRIDIZATION METHOD

机译:核酸,杂交试剂和核酸杂交方法的非特异性结合抑制剂

摘要

A non-specific-binding inhibitor enables, in detection of a target nucleic acid by hybridization, effective inhibition of cross-hybridization between the target nucleic acid and complementary strands of sequences similar thereto, which non-specific-binding inhibitor has a stable quality among production lots, and a hybridization method for nucleic acid uses the inhibitor. The non-specific-binding inhibitor for nucleic acid includes a nucleic acid which has a base length of 2 to 11 bases and in which the content of a guanine base(s) and/or methylated guanine base(s) in the entire base sequence is not less than 70%.
机译:在通过杂交检测靶核酸的检测中,有效抑制靶核酸和相似序列的互补链之间的交叉杂交的非特异性结合抑制剂能够实现,其中非特异性结合抑制剂具有稳定的质量 生产批次,核酸的杂交方法使用抑制剂。 核酸的非特异性结合抑制剂包括核酸,其碱基长度为2〜11个碱基,其中整个碱基序列中的鸟嘌呤碱基和/或甲基化鸟氨酸碱的含量 不低于70%。

著录项

  • 公开/公告号US2021395802A1

    专利类型

  • 公开/公告日2021-12-23

    原文格式PDF

  • 申请/专利权人 TORAY INDUSTRIES INC.;

    申请/专利号US201917288908

  • 发明设计人 TAKASHI SERIZAWA;

    申请日2019-10-29

  • 分类号C12Q1/6832;C12N15/11;

  • 国家 US

  • 入库时间 2024-06-14 22:34:45

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