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Non-specific binding inhibitors of nucleic acids, reagents for hybridization, and methods for hybridization of nucleic acids

机译:核酸的非特异性结合抑制剂,用于杂交的试剂,以及核酸杂交的方法

摘要

A non-specific binding inhibitor that effectively suppresses cross-hybridization between a target nucleic acid and a nucleic acid having a complementary sequence similar to that of a target nucleic acid when detecting a target nucleic acid by hybridization, and has stable quality between production lots, and a non-specific binding inhibitor using the same Methods for the hybridization of nucleic acids are disclosed. Non-specific binding inhibitors of nucleic acids include nucleic acids having a base length of 2 to 11 bases and a content of guanine bases or methylated guanine bases in the entire base sequence of 70% or more.
机译:当通过杂交检测靶核酸时,有效地抑制靶核酸与具有与靶核酸相似的核酸之间的核酸之间的交叉杂交的非特异性结合抑制剂。生产批次之间具有稳定的质量,公开了使用相同核酸杂交方法的非特异性结合抑制剂。核酸的非特异性结合抑制剂包括碱基长度为2至11个碱基的核酸,并且在整个碱基序列中的喹啉碱基或甲基化鸟嘌呤碱的含量为70%或更多。

著录项

  • 公开/公告号KR20210084352A

    专利类型

  • 公开/公告日2021-07-07

    原文格式PDF

  • 申请/专利权人 도레이 카부시키가이샤;

    申请/专利号KR20207037795

  • 发明设计人 세리자와 타카시;

    申请日2019-10-29

  • 分类号C12N15/113;C12Q1/6832;C12Q1/6876;

  • 国家 KR

  • 入库时间 2022-08-24 20:05:43

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