首页> 外国专利> COMPOSITION COMPRISING AGATHOBACULUM SP. STRAIN AS EFFECTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF AUTISM SPECTRUM DISORDER

COMPOSITION COMPRISING AGATHOBACULUM SP. STRAIN AS EFFECTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF AUTISM SPECTRUM DISORDER

机译:组合物包含agathobaculum sp。 菌株作为预防,缓解或治疗自闭症谱系障碍的有效成分

摘要

The present invention relates to anAgathobaculumsp. strain having prophylactic or therapeutic effects on autism spectrum disorders, and use thereof. When the intestinal microorganismAgathobaculumsp. strain of the present invention was orally administered to valproic acid (VPA)-induced autism model mice and BTBR autism model mice, the effects of remarkably improving autism spectrum disorders including repetitive behaviors, hyperactivity, social deficiency and cognitive/memory dysfunction of the mice were observed, as compared with a non-treated control. Accordingly, it may be usefully applied to foods, drugs, or feeds for preventing or treating autism spectrum disorders, and thus is very useful in the relevant industries.
机译:本发明涉及Anagathobaculumsp。 对自闭症谱系疾病具有预防或治疗效果的菌株,以及其用途。 当肠道微生物稗虫蛋白花。 将本发明的菌株口服给予丙戊酸(VPA)诱导的自闭症模型小鼠和BTBR自闭症模型小鼠,显着改善自闭症谱系疾病,包括重复行为,多动,社会缺乏和小鼠的认知/内存功能障碍 与未治疗的对照相比,观察到。 因此,可以有用处应用于用于预防或治疗自闭症谱紊乱的食物,药物或饲料,因此在相关行业中非常有用。

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