首页> 外国专利> Composition for preventing ameliorating or treating autism spectrum disorder comprising Agathobaculum sp. strain as effective component

Composition for preventing ameliorating or treating autism spectrum disorder comprising Agathobaculum sp. strain as effective component

机译:用于预防或改善自闭症谱系障碍的组合物,包括Agathobaculum sp.。应变为有效成分

摘要

The present invention relates to an Agathobaculum sp. strain having a preventive or therapeutic effect on autism spectrum disorders and a use thereof. As a result of orally administering an intestinal microorganism, the Agathobaculum sp. strain of the present invention to valproic acid (VPA)-induced autism model mice and BTBR autism model mice, the Agathobaculum sp. strain exhibits an effect of remarkably alleviating autism spectrum disorders including repetitive behavior, hyperactivity, difficulties with social interaction, and cognitive/memory impairment behavior, compared to a non-treated control. Therefore, the Agathobaculum sp. strain can be usefully used in food, medicine, or feed for preventing or treating autism spectrum disorders, thereby being very useful for related industries.
机译:本发明涉及一种农杆菌(Agathobaculum sp。)。对自闭症谱系障碍具有预防或治疗作用的毒株及其用途。由于口服施用肠道微生物,Agathobaculum sp.。本发明的菌株对丙戊酸(VPA)诱导的自闭症模型小鼠和BTBR自闭症模型小鼠Agathobaculum sp。与未治疗的对照组相比,该菌株表现出显着缓解自闭症谱系障碍的作用,包括重复性行为,活动过度,社交互动困难以及认知/记忆障碍行为。因此,Agathobaculum sp.。该菌株可有效地用于食品,药品或饲料中,以预防或治疗自闭症谱系障碍,因此对相关行业非常有用。

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