首页> 外国专利> COMPOSITION COMPRISING AGATHOBACULUM SP. STRAIN AS EFFECTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF AUTISM SPECTRUM DISORDER

COMPOSITION COMPRISING AGATHOBACULUM SP. STRAIN AS EFFECTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF AUTISM SPECTRUM DISORDER

机译:包含 AGATHOBACULUM SP的组合物。应变是预防,缓解或治疗自闭症谱系障碍的有效成分

摘要

The present invention relates to an Agathobaculum sp. strain having a preventive or therapeutic effect on autism spectrum disorders and a use thereof. The gut microorganism Agathobaculum sp. strain according to the present invention exhibits the effect of remarkably alleviating autism spectrum disorders including repetitive behavior, hyperactivity, difficulties with social interaction, and cognitive/memory impairment behavior in valproic acid (VPA)-induced autism model mice and BTBR autism model mice to which the strain has been orally administered, compared to a non-treated control, and thus can be effectively used in a food, a medicinal product, or foodstuff for preventing or treating autism spectrum disorders, finding very useful applications in related industries.
机译:本发明涉及一种 Agathobaculum 。对自闭症谱系障碍具有预防或治疗作用的毒株及其用途。肠道微生物 Agathobaculum 。在丙戊酸(VPA)诱发的自闭症模型小鼠和BTBR自闭症模型小鼠中,根据本发明的菌株显示出显着缓解自闭症谱系障碍的作用,包括重复性行为,活动过度,社交互动困难以及认知/记忆障碍行为。与未经治疗的对照相比,该菌株已经口服给药,因此可以有效地用于食品,药品或食品中以预防或治疗自闭症谱系障碍,在相关行业中发现非常有用的应用。

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