Polypeptide having a leukemia cell proliferation inhibitory action

摘要

The present invention discloses a polypeptide having a leukemia cell proliferation inhibitory action, and specifically relates to the application of the polypeptide in a drug for treating leukemia. The polypeptide consists of 37 amino acids, and the amino acid sequence is Lys-Glu-Ser-Met-Asp-Ala-Asn-Lys-Pro-Thr-Lys-Asn-Leu-Pro-Leu-Lys-Lys-Ile-Pro -Cys-Lys-Thr-Ser-Ala-Pro-Ser-Gln-Ser-Phe-Phe-Ala-Arg-Asp-Asn-Thr-Ala-Asn. The N-terminus of the polypeptide is linked to myristic acid, and the polypeptide prepared in the present invention enters into leukemia cells through linkage with myristic acid to realize the effect of inhibiting proliferation of leukemia cells.