METHOD OF USING ALLOGENEIC HAPLOIDENTICAL ADIPOSE TISSUE-DERIVED STROMAL VASCULAR FRACTION IN THE TREATMENT OF HUTCHINSON-GILFORD PROGERIA SYNDROME PATIENT

摘要

A composition for treating Hutchinson-Gilford progeria syndrome according to an embodiment of the present invention includes a stromal vascular fraction (SVF). The stromal vascular fraction (SVF) may be produced by a process including centrifuging an allogeneic haploidentical adipose tissue lipoaspirate to obtain a packed adipose tissue, mixing the packed adipose tissue with collagenase, mincing the packed adipose tissue mixed with the collagenase by using a homogenizer, incubating the minced adipose tissue, centrifuging the incubated adipose tissue to separate and remove the collagenase, and repeating the centrifuging to obtain the stromal vascular fraction. A method of treating a subject with Hutchinson-Gilford progeria syndrome according to an embodiment of the present invention includes preparing allogeneic haploidentical adipose tissue-derived stromal vascular fraction (SVF) from a donor without Hutchinson-Gilford progeria syndrome, and administering to the subject the allogeneic haploidentical adipose tissue-derived stromal vascular fraction.