AZA SEVEN-MEMBERED RING INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF

摘要

An aza seven-membered ring inhibitor, and a preparation method therefor and use thereof. Specifically, a compound has a structure represented by formula (I). Disclosed are a preparation method for the compound and the use of same as a KRASG12C inhibitor. The compound has a good selective inhibition effect on KRASG12C, and has better pharmacodynamic and pharmacokinetic performance, and lower toxic and side effects.