Hydrolysis of Phosphorodithioates with a Seven-membered Ring( Ⅰ )——Kinetics and Mechanism of Acidic Hydrolysis

摘要

Introduction The phosphorodithioate is an important organophosphate pesticide. The hydrolysis reactions are very important to the metabolism of the pesticides. There have been many papers published in this domain concerning the hydrolysis of organophosphate esters. Studies on the hydrolysis of phosphorodithioate esters with a seven-membered ring, however, have rarely been reported. O, O-biphenyl S-alkyl phosphorothiolothionates with notable biological activities have recently been synthesized. In the present pater, UV spectroscopic method and molecular orbital calculation are used to carry out a research into the kinetics and-mechanisms of their hydrolyses.