Title cpds. are of formula (I): where Z = an opt. substd., condensed aromatic, carbocyclic, or heterocyclic ring; R = H or 1-8C alkyl; X = O or S; Y = H, 1-8C alkyl, 1-8C alkanoyl, or -CO2(1-8C alkyl); and Z = Ph or thienyl. (I) are prepd. e.g., by condensing a 6-acylaminopenicillanic acid with a substd. pyridine-3-carboxylic acid.
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机译:标题cpds。具有式(I):其中Z =一个opt。稠合的芳族,碳环或杂环; R = H或1-8C烷基; X = O或S; Y = H,1-8C烷基,1-8C烷酰基或-CO2(1-8C烷基); Z = Ph或噻吩基。 (一)准备。例如,通过将6-酰基丙二酸与缩醛缩合。吡啶-3-羧酸。
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