Procedure for preparing tetrazol substituted derivatives. (Machine-translation by Google Translate, not legally binding)

摘要

Procedure for preparing substituted tetrazole derivatives of formula: **(See formula)** Wherein R1 is alkyl or alkoxy of 1 to 2 carbon atoms, R2 is alkyl or alkoxy of 1 to 2 carbon atoms, hydrogen, nitro or halogen, R3 is hydrogen or alkyl of 1 to 4 carbon atoms and n is 0, 1 or 2, and their pharmaceutically acceptable salts; characterized in that it comprises activating an 8-carboxyquinoline of the formula: **(See formula)** and make it react with an aminotetrazole of formula: **(See formula)** in which formulas R1, R2, R3 and n are defined as above; and recovering the desired compound; whereupon, if desired, the resulting compound is reacted with a basic compound to form a pharmaceutically acceptable salt thereof and the salt is recovered. (Machine-translation by Google Translate, not legally binding)