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PROCESS FOR PREPARING 2-AMINO-3- (HALOBENZOYL) -METHYLPHENYLACE- TIC ACIDS ESTERS AND SALTS THEREOF

机译:制备2-氨基-3-(卤代苯甲酰基)-甲基苯乙酸酯及其盐的方法

摘要

Novel 2-amino-3-(halobenzoyl)- methylphenylacetic acids, esters and salts having the formula: IMAGE wherein R represents a hydrogen atom, a lower alkyl group or a pharmaceutically acceptable metal cation, Y represents a halogen atom and n is an integer from 1 to 3 are provided. The compounds exhibit outstanding anti-inflammatory and analgesic activity in warm blooded animals with minimal gastro-intestinal toxicity.
机译:具有下式的新型2-氨基-3-(卤代苯甲酰基)-甲基苯基乙酸,酯和盐:其中R代表氢原子,低级烷基或可药用的金属阳离子,Y代表卤原子,n为提供1到3之间的整数。该化合物在温血动物中表现出出色的抗炎和镇痛活性,对胃肠道的毒性也最小。

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