首页> 外国专利> A procedure for preparing pirrolidine-derived diasterisomers (Machine-translation by Google Translate, not legally binding)

A procedure for preparing pirrolidine-derived diasterisomers (Machine-translation by Google Translate, not legally binding)

机译:制备吡咯烷衍生的非对映异构体的过程(通过Google翻译进行机器翻译,没有法律约束力)

摘要

Procedure to prepare dietries derived from 1-ethyl-2-aminomethyl pyrrolidine. 1-ethyl-2-aminometilpirrolidine racemica is dissolved in aqueous methanol and is treated with acid (-) - di-p-toluoil-l-tartaric with which crystallizes (-) - di-p-toluoil-l-tartrate of levo-1-ethyl-2-aminomethylprolroline and is isolated and the (-) - di-p-toluoil-l-tartrate dextro-1-ethyl-2- aminometilpirrolidin remains in mothers or is treated 1-ethyl-2-aminometilpir rolidine racemica with acid (-) - di-p-toluoil-l-tartaric in methanol with what crystallizes (-) - di-p-toluoil-l- dextro-1-ethyl-2-aminomethylprolrolineine tartrate and is isolated after which the addition of water to methanol's waters gives as a result the crystallization of (-) - di-p-toluoil-l-tartrate of levo-1 -etil-2-amcnometilpi rrolidina.se is used as an intermediate compound in the manufacture of pharmaceutical products. (Machine-translation by Google Translate, not legally binding)
机译:制备衍生自1-乙基-2-氨基甲基吡咯烷的饮食的程序。将1-乙基-2-氨基甲吡咯烷消旋体溶解在甲醇水溶液中,然后用酸(-)-二对甲苯基-1-酒石酸处理,使其结晶(-)-二对甲苯基-1-酒石酸左旋酒石酸盐。分离1-乙基-2-氨基甲基脯氨酰基,将(-)-二对甲苯甲-1-酒石酸右-1-乙基-2-氨基甲吡咯烷酮残留在母亲体内,或将1-乙基-2-氨基甲吡咯烷消旋消旋体与酸(-)-甲醇中的二对甲苯酚-1-酒石酸结晶(-)-酒石酸二-对甲苯酚-1-右旋-1-乙基-2-氨基甲基脯氨酯碱,在分离后加入水甲醇水中生成的左旋1-etil-2-amcnometilpi rrolidinase的(-)-二对甲苯酚-1-酒石酸盐的结晶.se用作药物生产中的中间体。 (通过Google翻译进行机器翻译,没有法律约束力)

著录项

  • 公开/公告号ES8405370A1

    专利类型

  • 公开/公告日1984-06-01

    原文格式PDF

  • 申请/专利权人 ASTRA PHARMACEUTICAL PRODUCTION AB;

    申请/专利号ES19830526077

  • 发明设计人

    申请日1983-09-29

  • 分类号C07D207/09;

  • 国家 ES

  • 入库时间 2022-08-22 09:05:42

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号