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Process for the (alpha) -c-alkylation 8-acyl group of mevinolin and analogs thereof.
Process for the (alpha) -c-alkylation 8-acyl group of mevinolin and analogs thereof.
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机译:米维诺林及其类似物的α-c-烷基化8-酰基的方法。
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摘要
A process for alkylating the alpha position of the 8-acyl side chain in mevinolin and analogs thereof is disclosed. The process proceeds with a single charge of base and alkyl halide to give products with a pharmaceutically acceptable purity.
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