PROCESS FOR PREPARING CINNAMOYL-13ALPHA BACCATIN III OR DESACETYL-10 BACCATIN III

摘要

Process for the preparation of cinnamoyl-13alpha baccatin III or 10-deacetyl baccatin III of formula (I) by condensation of a mixed anhydride of general formula (II) on a derivative of baccatin III or of 10-deacetyl baccatin III of general formula (III). BR/ In formulas (I) and (III), R1 represents an acetyl or 2,2,2-trichloroethoxycarbonyl radical. BR/ In formula (II), R represents 1 to 5 substituents, identical or different (halogen, nitro, methyl, methoxy). BR/ (CF DRAWING IN BOPI) BR/