11-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions

摘要

The present invention is concerned with novel 11-methylene- oestr-15- enes of the formula: ##STR1## wherein R.sub.1 =H or acyl with 1- 18 C- atoms, preferably H,PPR.sub.2 =ethinyl, vinyl, chloroethinyl, allyl or propinyl; ethinyl being preferred, andP PR.sub.3 =O or H.sub.2, preferably O.PPFurther the present invention is concerned with processes for the preparation of the above compounds and with pharmaceutical compositions comprising these compounds. The compounds possess powerful gestagenic properties and only slight androgenic side-effects.