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CARCINOGENIC PROMOTION-INHIBITING COMPOSITION

机译:致癌促进抑制成分

摘要

PURPOSE: To obtain a carcinogenic promotion-inhibiting composition containing the extract of Citrus hystrix, an edible plant grown in Thai, as an active ingredient and useful for foods, cosmetics and medicines such as anticancer agents which inhibit the generation of tumors or cancers. ;CONSTITUTION: This carcinogenic promotion-inhibiting composition contains the extract of Citrus hystrix (especially leaves), an edible plant grown in Thai, especially its extract with a hydrophilic organic solvent (preferably a polar organic solvent), as an active ingredient. The composition can be prepared into foods, cosmetics and medicines such as antitumor agents. The active ingredient of the extract of the Citrus hystrix is a compound of the formula (R1, R2 are α-linolenoyl, palmitoyl). The extract of the Citrus hystrix is useful as a carcinogenic promotion-inhibiting ingredient, because of strongly inhibiting the activation of EBV with teleocidin B-4, a promoter, and is highly safe because of being originated from the edible material.;COPYRIGHT: (C)1994,JPO
机译:用途:获得一种抑制癌变的促进剂组合物,其中含有柑桔(Citrus hystrix)的提取物(一种在泰国种植的食用植物)作为有效成分,可用于食品,化妆品和药物,例如抑制肿瘤或癌症产生的抗癌剂。 ;组成:这种抑制致癌作用的组合物含有柑桔提取物(特别是叶子)(一种在泰国种植的食用植物),尤其是其提取物与亲水性有机溶剂(最好是极性有机溶剂)的有效成分。该组合物可以制备成食品,化妆品和药物,例如抗肿瘤剂。柑桔提取物的活性成分为下式的化合物(R 1 ,R 2 为α-亚麻酸,棕榈酰)。柑桔提取物可用作致癌促进抑制成分,因为它通过启动子teleoocidin B-4强烈抑制EBV的活化,并且由于其源自可食用材料而非常安全。 1994)日本特许厅

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