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Process for the preparation and the use of monoclonal antibodies against X or Y chromosome-containing sperm for separating spermatozoa

机译:含X或Y染色体精子的单克隆抗体的制备及其分离精子的方法

摘要

Rapid and efficient separation of intact male and female sperm is desirable and necessary in many areas. The success of this has been only inadequate to date. Rapid and reliable separation of intact sperm is possible using monoclonal antibodies with selective specificity either for male or female spermatozoa. By using a ring-like pessary coated with monoclonal antibodies, parents are able to determine freely the sex of their offspring and need no longer leave this to chance. Furthermore, in agriculture it is possible before the artificial insemination of cattle, pigs etc. to separate the sperm rapidly and reliably into male and female spermatozoa.
机译:快速而有效地分离完整的雄性和雌性精子在许多领域都是理想且必要的。迄今为止,这种方法的成功还不够。使用对男性或女性精子具有选择性特异性的单克隆抗体,可以快速可靠地分离完整的精子。通过使用涂有单克隆抗体的环状子宫托,父母们可以自由地确定其后代的性别,而不再需要碰碰运气了。此外,在农业中,有可能在人工授精牛,猪等之前将精子迅速而可靠地分离为雄性和雌性精子。

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