首页> 外国专利> Pyrrolidine derivatives substituted in the 3-position with a saturated or insaturated fatty acid group, process for their preparation and pharmaceuticals with thromboxane A2 inhibiting activity containing them

Pyrrolidine derivatives substituted in the 3-position with a saturated or insaturated fatty acid group, process for their preparation and pharmaceuticals with thromboxane A2 inhibiting activity containing them

机译:在3位上被饱和或不饱和脂肪酸基团取代的吡咯烷衍生物,其制备方法以及具有血栓烷A2抑制活性的药物

摘要

Compounds of formula (I): IMAGE in which: R1 represents: - an optionally substituted alkyl group, - an optionally substituted phenyl group, - a pyridyl group, - an optionally substituted phenylsulphonyl group, - an acyl group, - an optionally substituted benzoyl or pyridylcarbonyl group, - an alkylaminocarbonyl or phenylaminocarbonyl group, - an acylamino or benzoylamino group, R2 represents: - a hydrogen atom, - an optionally substituted phenyl group, - an optionally substituted 3-pyridyl or 2-pyridyl group, R3 represents any one of the following groups: IMAGE IMAGE - (CH2)n-CO2R in which - m is equal to 2, 3 or 4, - n is equal to 4, 5, 6 or 7, and R represents a hydrogen atom or an alkyl group. Medicaments.
机译:式(I)的化合物:<图像>其中:R1代表:-任选取代的烷基,-任选取代的苯基,-吡啶基,-任选取代的苯基磺酰基,-酰基,-任选取代的苯甲酰基或吡啶基羰基,-烷基氨基羰基或苯氨基羰基,-酰基氨基或苯甲酰基氨基,R2代表:-氢原子,-任选取代的苯基,-任选取代的3-吡啶基或2-吡啶基,R3代表以下任何一组: -(CH2)n-CO2R,其中-m等于2、3或4,-n等于4、5、6或7,R代表a氢原子或烷基。药物。

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