DERIVATIVES OF QUINOLINECARBOXYLIC ACID AND BORIC ACID ANHYDRIDE AND PROCESS FOR PRODUCING THEM

摘要

The derivatives closed to anhydride of quinolinecarboxylic acid and boric acid with a general formula (I), where the symbol R means a cyclopropyl group, the symbols R1 and R2 which can be of the same or of the different meaning and mean halogen, aliphatic acyloxy group containing 2 up to 6 carbon atoms, or a substituted one by halogen or aromatic acyloxy group with 7 up to 11 carbon atoms, the symbol R3 means chlorine and the symbol R4 means hydrogen, can be prepared based on 1-substitued-6- -fluoro-7-substitued-4-oxoderivatives of anhydride closed to 1,4-dihydro-quinoline-3-carboxylic acid which can be substituted with fluorine in the position 8 according to the reaction with triacylborane derivative with a general formula (V), where the symbol R9 means alkyl group containing 1 up to 5 carbon atoms, while this group can be substituted with halogen or the aryl rest containing 6 up to 10 carbon atoms.