PROCESS FOR PRODUCING ASPARTASE AND PROCESS FOR PRODUCING L-ASPARTIC ACID

摘要

Disclosed are a process for producing aspartase whichcomprises culturing a microorganism belonging to the genusEscherichia being capable of producing aspartase in a mediumuntil aspartase is produced and accumulated in the culture, andrecovering aspartase therefrom, wherein dissolved oxygenconcentration of the medium is in the range of 0 to 1 ppm onthe stage that microbial growth is middle and/or latelogarithmic growth phase; and a process for producingL-aspartic acid which comprises converting fumaric acid andammonia into L-aspartic acid in an aqueous medium in the presenceof an enzyme source, wherein said enzyme source is a cultureproduced in accordance with said aspartase-producing process,cells isolated from the culture, or processed cells thereof.