2-mercaptobenzimidazole derivatives having pharmacological activity

摘要

2-mercaptobenzimidazole derivatives of the general formula CHEM wherein: N = 0,2,3; R - hydrogen atom, aralkyls; R1 - lower alkyls, alkenyls, dialkylamino, a saturated amine monocyclic residue which may contain an additional heteroatom; R2 and R3 are equal or different and stand for hydrogen atoms, lower alkyls, alkoxy in various positions, and their phatmaceutically acceptable salts, according to the results of pharmacological research study exhibit a pronounced anxiolytic, sedative, antiischemia and antiarrhythmia effect and have certain advantages over popular clinic preparations. These can find a wide variety of application for treatment of patients suffering from various mental derangements and heart ischemia.