QUINOLINE DERIVATIVE, ANTIULCER DRUG CONTAINING THE SAME, AND PRODUCTION OF SAID DERIVATIVE

摘要

A quinoline derivative of general formula (I) and its salt, useful as an antiulcer drug, wherein R1 represents lower alkoxy, halogen, lower alkyl, lower alkylthio, lower alkanoyloxy-substituted lower alkyl, halogenated lower alkyl or hydroxylated lower alkyl; R2 and R3 may be the same or different from each other and each represents hydrogen, lower alkyl, halogenated lower alkyl, C3 to C8 cycloalkyl, cycloalkyl-substituted lower alkyl, lower alkenyloxy, lower alkenyl, lower alkoxy-substituted lower alkyl, phenyl-substituted lower alkyl, lower alkynyl, lower alkylphenyl or hydroxylated lower alkyl; R4 represents phenyl, tetrahydronaphthyl or naphthyl which may be each substituted with one or two members selected from the group consisting of lower alkyl, halogen, lower alkoxy, lower alkylthio, lower alkanoyl, phenyl, cyano, lower alkynylsulfinyl, lower alkoxycarbonyl, lower alkenylthio, phenyl-substituted lower alkylthio, benzoyl, hydroxylated lower alkyl, lower alkanoyloxy-substituted lower alkyl, lower alkanoyloxy and hydroxyl; and n is 0, 1 or 2.