The present invention relates to a method of preparation of transgenic plants resistant to viral infections by introducing into the genoma of a host plant an antisense gene construct constituted by: the domain F of the subgenomic promoter of a viral RNA; a leader sequence of a viral ORF, downstream from said subgenomic promoter; the gene encoding a viral coat protein, downstream from said leader sequence; and the 3'-terminal region of a viral RNA, downstream from said gene. The present invention also relates to a recombinant vector comprising a promoter functional in a host plant, and, operably linked to this promoter, the antisense gene construct of the present invention.
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