Tryptophan - analogs in proteins, peptides and peptide guide structures.

摘要

The present invention relates to proteins, peptides and peptidic basic structures, based on the incorporation of tryptophan - amino acid analogs, in particular of chalcogen - and / or halogen - analogs, new kirstallographische, spectral and / or pharmacological properties. Furthermore, the invention relates to a process for the marking of proteins, peptides and peptide guide structures, in which these by the incorporation of amino acid - analogues with new crystallographic and / or spectral properties are provided. Furthermore, the invention relates to a method for determining the three-dimensional structure of proteins, peptides or peptide guide structures by means of crystal structure analysis. Finally, the invention relates to pharmaceutical compositions containing as active ingredient at least a tryptophan - analogue, which in a carrier, for example, a protein, a peptide, or a peptidic guide structure, is installed.