Methods of treatment or prophylaxis of an individual's inflammatory condition and immunoprotection, composition, computer and computer program product, process of separating macrocyclic diterpenes from a biomass and use of chemical or derivative agent or chemical analog of that

摘要

"METHODS OF TREATMENT OR PROPHILAXY OF INFLAMMATORY CONDITION AND IMMUNITY PROTECTION" COMPUTER, COMPUTER, AND PRODUCT OF COMPUTER PROGRAM, PROCESS OF SEPARATING MACROCYCLIC DIFFERENCIES OR DIFFERENTIAL DYNAMICS The present invention relates generally to chemical agents useful in the treatment and prophylaxis of protein C kinase (PKC) linked to certain conditions in mammals, including humans and primates, non-mammalian animals and bird species. More specifically, the present invention provides a chemical agent of the macrocyclic diterpene family obtainable from a member of the Euphorbia plant family or its botanical or horticultural derivatives or chemical derivatives or analogues or chemically synthetic forms of the agents. used in the treatment or prophylaxis of PKC-related conditions in mammals, animals and birds. The chemical agents in question are also useful for modulating the expression of genetic sequences including promotion and other regulatory sequences. The present invention also contemplates a method for prophylaxis and / or treatment in mammalian, animal and bird subjects that exhibit PKC-linked conditions by the topical or systemic administration of macrocyclic diterpenes, obtainable from a member of the Euphorbia family of plants or from its botanical or horticultural derivatives or from a chemical analog derivative or chemically synthetic form of the agent. The chemical agent of the present invention may be in the form of a purified compound, a mixture of compounds, a precursor of one or more of the compounds capable of chemically transforming into a therapeutically and / or genetically active agent or in the form of a chemical fraction, subfraction, preparation or extract of the plant.