首页> 外国专利> 'method of treating an inflammatory condition in an individual in need thereof, method of selecting an individual for the treatment or otherwise of an inflammatory condition with an anti-inflammatory agent or an anticoagulant agent, method of selecting a group of individuals' to determine the efficacy of a known or suspected candidate drug to be useful for treating an inflammatory condition, method for increasing the likelihood of efficacy of a protein c treatment or a treatment with a protein c-like compound, method for identifying a an individual who has one or more serious adverse event, enhanced response, risk, or reduced serious adverse event genotype (s), use of an anti-inflammatory agent, or an anticoagulant agent in the manufacture of a medicament for treating an inflammatory condition. in a subset of individuals, commercial package, two or more oligonucleotides or nucleic acids from from about 10 to about 400 nucleotides, array of oligonucleotides or peptide nucleic acids atta

'method of treating an inflammatory condition in an individual in need thereof, method of selecting an individual for the treatment or otherwise of an inflammatory condition with an anti-inflammatory agent or an anticoagulant agent, method of selecting a group of individuals' to determine the efficacy of a known or suspected candidate drug to be useful for treating an inflammatory condition, method for increasing the likelihood of efficacy of a protein c treatment or a treatment with a protein c-like compound, method for identifying a an individual who has one or more serious adverse event, enhanced response, risk, or reduced serious adverse event genotype (s), use of an anti-inflammatory agent, or an anticoagulant agent in the manufacture of a medicament for treating an inflammatory condition. in a subset of individuals, commercial package, two or more oligonucleotides or nucleic acids from from about 10 to about 400 nucleotides, array of oligonucleotides or peptide nucleic acids atta

机译:“在有需要的个体中治疗炎性疾病的方法,用抗炎剂或抗凝剂选择用于治疗或以其他方式治疗炎性疾病的方法,选择一组个体的方法”来确定已知或疑似候选药物可用于治疗炎性疾病的功效,提高蛋白c治疗功效或使用蛋白c样化合物治疗的可能性的方法,鉴定患有以下疾病的个体的方法更严重的不良事件,增强的反应,风险或减少的严重不良事件基因型,在治疗炎症性疾病的药物生产中使用抗炎剂或抗凝剂。在一个个体的子集中,商业包装中,两个或多个寡核苷酸或核酸从约10个到约400个核苷酸,寡核苷酸或肽核酸的阵列

摘要

Methods, oligonucleotides arrays etc. for treating inflammatory conditions and of predicting subject outcome based on polymorphisms in SERPINE1 and/or PROC, alone or in combination, wherein the method of treatment includes administering to the subject an anti-inflammatory agent or an anti-coagulant agent, wherein said subject is determined to have an improved response genotype or combination.
机译:单独或组合用于治疗炎症性疾病和基于SERPINE1和/或PROC中的多态性预测受试者结果的方法,寡核苷酸阵列等,其中治疗方法包括向受试者施用抗炎剂或抗凝剂试剂,其中确定所述受试者具有改善的反应基因型或组合。

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