Site-directed recombinase fusion proteins and corresponding polynucleotides, vectors and kits, and their uses for site-directed DNA recombination

摘要

The invention relates to fusion proteins comprising a site-directed recombinase protein and a heterologous protein that binds either directly or indirectly DNA at at least one responsive element, said fusion protein having at least a heterologous site-directed recombinase activity. The invention also relates to the corresponding polynucleotides, vector and kits. The invention also provides methods for site-directed DNA recombination and for the stable introduction a DNA sequence of interest into a recipient DNA molecule.